Southeast Columbia Real Estate View 113 listings HomeGuidesSoutheast Columbia Southeast Columbia is an expanding area on the southeast side of Columbia going down 78 towards Sumter, SC. This makes up where Lower Richland High School is and Hopkins and Eastover. See all home listings in Southeast Columbia here. Guides SanteeLake MurrayLexingtonBlythewoodIrmoChapinDowntown ColumbiaWest Columbia / CayceNortheast ColumbiaSoutheast ColumbiaElgin / Lugoff